个人简历
1972.12出生,医学博士,教授,主任医师,博士生导师, 1996.7至今于广东医科大学附属医院工作,期间2002.9-2005.7于广东医科大学攻读重症医学硕士研究生,2006.9-2009.7于南方医科大学攻读心血管内科学博士研究生,2018.10-2018.12于意大利Carrige大学附属医院短期进修学习。中国研究型医院学会休克与脓毒症专业委员会委员,中国人体健康科技促进会重症医学与器官支持专委会委员,广东省医学会重症医学分会常务委员,广东省病理生理学会重症医学分会副主任委员,广东省基层医药会重症医学分会副主任委员,湛江市医学会重症医学分会主任委员,广东医科大学附属医院高层次人才。
近5年主持课题:
国家自然科学基金面上项目:项目名称:中性粒细胞外泌体miR-150-5p靶向TREM-1抑制心肌细胞焦亡的机制及其在脓毒性心肌病中作用,第一负责人,项目时间:2022-2025;项目编号:82172148
国家自然科学基金面上项目:项目名称:TREM-1/SMC4/NEMO通路激活NLRP3炎症小体分子机制及其在脓毒性心肌病中作用,第一负责人,项目时间:2020-2024;项目编号:81974298
广东省科技攻关应急专项科研项目:项目名称:干扰素α-2b联合洛匹那韦/利托那韦治疗新型冠状病毒肺炎疗效的多中心随机对照研究,第一负责人,项目时间:2020.02-2022.12;项目编号:2020A111135049
近5年发表文章
Zilong Yang , Xiaoyan Pan , Xiaoxia Wu , Qiuyun Lin , Yongxia Chen , Shuting Cai , Yuanli Zhang , Zhenhua Mai , Niall Ahmad , Daqing Ma※, Liehua Deng※(邓烈华).TREM-1 induces pyroptosis in cardiomyocytes by activating NLRP3 inflflammasome through the SMC4/ NEMO pathway. FEBS J. 2022 Oct 1.doi: 10.1111/febs.16644. Online ahead of print(共同通讯作者 IF=5.622 JCR 2区)
Yiyue Zhong # , Liehua Deng #(邓烈华) , Limin Zhou, Shaoling Liao, Liqun Yue, Shi Wu Wen, Rihua Xie, Yuezhen Lu, Liangqing Zhang, Jing Tang, Jiayuan Wu. Association of immediate reinsertion of new catheters with subsequent mortality among patients with suspected catheter infection: a cohort study. Ann Intensive Care. 2022, 07;12(1):38.(并列第一作者 IF=10.318 JCR 1区)
Zhuohao Xie, Peng Li, Haonan Zhan, Liuyan Zhuang, Sijian Tao, Liehua Deng※(邓烈华), Jiahao Huang※. Rational design of an allosteric G-quadruplex aptamer probe for ultra-sensitive detection of melamine in milk.Int J Biol Macromol .2022,15;210.430-438.(共同通讯作者 IF=8.025 JCR 1区)
Peng Li, Wenqin Li, Zhuohao Xie, Haonan Zhan, Liehua Deng※(邓烈华), Jiahao Huang※.A label-free and signal-amplifiable assay method for colorimetric detection of carcinoembryonic antigen. Biotechnol Bioeng. 2022 ,119(2):504-512.(共同通讯作者 IF=4.395 JCR 2区)
Chen HP, Wang XY, Pan XY, Hu WW, Cai ST, Joshi K, Deng LH※(邓烈华), Ma D※. Circulating neutrophil-derived microparticles associated with the prognosis of patients with sepsis. J Inflamm Res. 2020;13: 1113–1124(共同通讯作者 IF=6.92 JCR 2区)
Liehua Deng(邓烈华), Shaoqing Lei, Xiaoyan Wang, Fang Jiang, David A Lubarsky, Liangqing Zhang, Danyong Liu, Conghua Han, Dunrong Zhou, Zheng Wang, Xiaocong Sun, Yuanli Zhang, Chi Wai Cheung, Sheng Wang, Zhongyuan Xia, Richard L Applegate, Jing Tang, Zhenhua Mai※, Hong Liu※, Zhengyuan Xia※.Course of illness and outcomes in older COVID-19 patients treated with HFNC: a retrospective analysis. Aging (Albany NY). 2021 , 28;13.(共同第一作者 IF=5.682 JCR 2区)
Yiyue Zhong . Limin Zhou . Xiaolei Liu . Liehua Deng※(邓烈华) . Ruona Wu . Zhengyuan Xia . Guixi Mo . Liangqing Zhang . Zhifeng Liu . Jing Tang.Incidence, RiskFactors,and Attributable Mortality of Catheter-Related BloodstreamInfections inthe Intensive Care Unit After Suspected Catheters Infection:A Retrospective 10-year Cohort Study. Infect Dis Ther. 2021;10(2): 985–999(共同通讯作者 IF=5.32 JCR 2区)
Rongzong Ye, Qiuyun Lin, Wenkai Xiao, Lixia Mao, Pengfei Zhang, Lingshan Zhou, Xiaoxia Wu, Nannan Jiang, Xihe Zhang, Yinhua Zhang, Daqing Ma, Jiahao Huang*, Xiaoyan Wang*, Liehua Deng*. miR-150-5p in neutrophil-derived extracellular vesicles associated with sepsis-induced cardiomyopathy in septic patients. Cell Death Discov. 2023;9(1):19.(共同通讯作者 IF=7.109 JCR 2区)
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